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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAGE
All Species:
9.39
Human Site:
S317
Identified Species:
18.79
UniProt:
Q9UQ07
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ07
NP_055041.1
419
48014
S317
A
P
E
P
L
S
N
S
C
Q
I
S
K
E
G
Chimpanzee
Pan troglodytes
XP_510176
419
47983
S317
A
P
E
P
L
S
N
S
C
Q
I
S
K
E
G
Rhesus Macaque
Macaca mulatta
XP_001112517
461
52662
S358
A
P
E
P
L
T
T
S
C
Q
I
S
K
E
G
Dog
Lupus familis
XP_547985
458
51843
G357
A
P
E
L
L
R
N
G
W
Q
I
S
K
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVS4
420
48046
N317
V
P
E
S
S
S
H
N
W
S
F
S
Q
E
G
Rat
Rattus norvegicus
Q62726
629
70550
L421
D
W
A
D
L
A
D
L
D
F
S
S
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
H205
A
T
K
K
P
L
F
H
G
D
S
E
I
D
Q
Frog
Xenopus laevis
NP_001084801
411
47114
Y312
N
T
S
G
S
M
N
Y
F
L
R
I
A
G
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23573
314
35870
Y216
D
S
E
I
D
Q
L
Y
R
I
F
R
T
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786078
440
50923
N332
G
K
D
G
D
N
D
N
H
K
A
V
R
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
F332
N
R
E
P
E
E
C
F
L
G
L
T
L
A
V
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
C200
V
D
T
W
S
I
G
C
I
F
A
E
M
C
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
82.6
76.6
N.A.
83.5
27.8
N.A.
N.A.
28.6
63.2
N.A.
N.A.
26.7
N.A.
N.A.
50.6
Protein Similarity:
100
99.5
85.2
81.2
N.A.
89.5
42.4
N.A.
N.A.
43.9
73.2
N.A.
N.A.
42.7
N.A.
N.A.
68.4
P-Site Identity:
100
100
86.6
66.6
N.A.
40
13.3
N.A.
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
66.6
N.A.
60
26.6
N.A.
N.A.
20
6.6
N.A.
N.A.
6.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
28.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.6
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
9
0
0
9
0
0
0
0
17
0
9
9
9
% A
% Cys:
0
0
0
0
0
0
9
9
25
0
0
0
0
9
0
% C
% Asp:
17
9
9
9
17
0
17
0
9
9
0
0
0
9
9
% D
% Glu:
0
0
59
0
9
9
0
0
0
0
0
17
0
42
0
% E
% Phe:
0
0
0
0
0
0
9
9
9
17
17
0
0
0
0
% F
% Gly:
9
0
0
17
0
0
9
9
9
9
0
0
0
9
34
% G
% His:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
0
0
9
9
34
9
9
0
0
% I
% Lys:
0
9
9
9
0
0
0
0
0
9
0
0
34
9
0
% K
% Leu:
0
0
0
9
42
9
9
9
9
9
9
0
9
17
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% M
% Asn:
17
0
0
0
0
9
34
17
0
0
0
0
0
0
9
% N
% Pro:
0
42
0
34
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
34
0
0
9
0
17
% Q
% Arg:
0
9
0
0
0
9
0
0
9
0
9
9
9
0
0
% R
% Ser:
0
9
9
9
25
25
0
25
0
9
17
50
9
0
9
% S
% Thr:
0
17
9
0
0
9
9
0
0
0
0
9
9
0
9
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
9
0
9
0
0
0
0
17
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _